HDMX regulates p53 activity and confers chemoresistance to 3-Bis(2-chloroethyl)-1-nitrosourea

Glioblastoma multiforme (GBM) is one of the deadliest tumors afflicting humans, and the mechanisms of its onset and progression remain largely undefined. Our attempts to elucidate its molecular pathogenesis through DNA copy-number analysis by genome-wide digital karyotyping and single nucleotide pol...

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Autori principali: Jin, Genglin, Cook, Stephen, Cui, Bo, Chen, William C., Keir, Stephen T., Killela, Patrick, Di, Chunhui, Payne, Cathy A., Gregory, Simon G., McLendon, Roger, Bigner, Darell D., Yan, Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940701/
https://ncbi.nlm.nih.gov/pubmed/20472715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq045
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