HDMX regulates p53 activity and confers chemoresistance to 3-Bis(2-chloroethyl)-1-nitrosourea

Glioblastoma multiforme (GBM) is one of the deadliest tumors afflicting humans, and the mechanisms of its onset and progression remain largely undefined. Our attempts to elucidate its molecular pathogenesis through DNA copy-number analysis by genome-wide digital karyotyping and single nucleotide pol...

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Detalhes bibliográficos
Main Authors: Jin, Genglin, Cook, Stephen, Cui, Bo, Chen, William C., Keir, Stephen T., Killela, Patrick, Di, Chunhui, Payne, Cathy A., Gregory, Simon G., McLendon, Roger, Bigner, Darell D., Yan, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940701/
https://ncbi.nlm.nih.gov/pubmed/20472715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq045
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