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Activation of the Hedgehog pathway in pilocytic astrocytomas

Pilocytic astrocytoma is commonly viewed as a benign lesion. However, disease onset is most prevalent in the first two decades of life, and children are often left with residual or recurrent disease and significant morbidity. The Hedgehog (Hh) pathway regulates the growth of higher WHO grade gliomas...

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Autors principals: Rush, Sarah Z., Abel, Ty W., Valadez, Juan G., Pearson, Matthew, Cooper, Michael K.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940682/
https://ncbi.nlm.nih.gov/pubmed/20223881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq026
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