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Activation of the Hedgehog pathway in pilocytic astrocytomas

Pilocytic astrocytoma is commonly viewed as a benign lesion. However, disease onset is most prevalent in the first two decades of life, and children are often left with residual or recurrent disease and significant morbidity. The Hedgehog (Hh) pathway regulates the growth of higher WHO grade gliomas...

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Detalhes bibliográficos
Main Authors: Rush, Sarah Z., Abel, Ty W., Valadez, Juan G., Pearson, Matthew, Cooper, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940682/
https://ncbi.nlm.nih.gov/pubmed/20223881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq026
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