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Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study
Immunostimulating oligodeoxynucleotides containing CpG motifs (CpG-ODN) have shown promising efficacy in cancer models when injected locally. In a phase I clinical trial, intratumoral infusions of CpG-ODN in glioblastoma (GBM) patients were well tolerated at doses up to 20 mg. This phase II trial wa...
Gorde:
Egile Nagusiak: | , , , , , , , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Oxford University Press
2010
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940609/ https://ncbi.nlm.nih.gov/pubmed/20308317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop047 |
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