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Akt2 and Akt3 play a pivotal role in malignant gliomas
Akt, one of the major downstream effectors of phosphatidylinositol 3-kinase, is hyper-expressed and activated in a variety of cancers including glioblastoma. However, the expression profiles of the Akt isoforms Akt1/PKBα, Akt2/PKBβ, and Akt3/PKBγ and their functional roles in malignant glioma are no...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940586/ https://ncbi.nlm.nih.gov/pubmed/20167810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop026 |
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