Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma

Glioblastoma (GB) is the most common malignant brain tumor in adults. It has limited treatment opportunities and is almost exclusively fatal. Owing to the central role the insulin-like growth factor-1 receptor (IGF-1R) plays in malignant cells, it has been suggested as a target for anticancer therap...

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Autors principals: Yin, Shucheng, Girnita, Ada, Strömberg, Thomas, Khan, Zahidul, Andersson, Sandra, Zheng, Huiyuan, Ericsson, Christer, Axelson, Magnus, Nistér, Monica, Larsson, Olle, Ekström, Tomas J., Girnita, Leonard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Rapid Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940558/
https://ncbi.nlm.nih.gov/pubmed/20150364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop008
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