Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma

Glioblastoma (GB) is the most common malignant brain tumor in adults. It has limited treatment opportunities and is almost exclusively fatal. Owing to the central role the insulin-like growth factor-1 receptor (IGF-1R) plays in malignant cells, it has been suggested as a target for anticancer therap...

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Detalhes bibliográficos
Main Authors: Yin, Shucheng, Girnita, Ada, Strömberg, Thomas, Khan, Zahidul, Andersson, Sandra, Zheng, Huiyuan, Ericsson, Christer, Axelson, Magnus, Nistér, Monica, Larsson, Olle, Ekström, Tomas J., Girnita, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Rapid Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940558/
https://ncbi.nlm.nih.gov/pubmed/20150364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop008
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