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Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation

Adrenocortical carcinoma (ACC) is a very aggressive tumor with a poor prognosis. Available treatments for this type of cancer are far from being satisfactory. The IGF signalling pathway represents an important mechanism for ACT growth and constitutes a relevant therapeutic target. We investigated th...

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Detalhes bibliográficos
Main Authors: Doghman, Mabrouka, Axelson, Magnus, Lalli, Enzo
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180063/
https://ncbi.nlm.nih.gov/pubmed/21968616
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