Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma

Glioblastoma (GB) is the most common malignant brain tumor in adults. It has limited treatment opportunities and is almost exclusively fatal. Owing to the central role the insulin-like growth factor-1 receptor (IGF-1R) plays in malignant cells, it has been suggested as a target for anticancer therap...

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Autori principali: Yin, Shucheng, Girnita, Ada, Strömberg, Thomas, Khan, Zahidul, Andersson, Sandra, Zheng, Huiyuan, Ericsson, Christer, Axelson, Magnus, Nistér, Monica, Larsson, Olle, Ekström, Tomas J., Girnita, Leonard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Rapid Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940558/
https://ncbi.nlm.nih.gov/pubmed/20150364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop008
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