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Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections.

Allogeneic mouse islets or xenogeneic rat islets, or fetal porcine islets were implanted under the renal capsule of C57BL/6 mice either alone or carefully mixed with syngeneic islets. With this experimental model the syngeneic islets, although not rejected themselves, are exposed to cytokines and in...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Korsgren, O, Jansson, L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117063
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