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Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections.

Allogeneic mouse islets or xenogeneic rat islets, or fetal porcine islets were implanted under the renal capsule of C57BL/6 mice either alone or carefully mixed with syngeneic islets. With this experimental model the syngeneic islets, although not rejected themselves, are exposed to cytokines and in...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Korsgren, O, Jansson, L
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117063
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