Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections.

Allogeneic mouse islets or xenogeneic rat islets, or fetal porcine islets were implanted under the renal capsule of C57BL/6 mice either alone or carefully mixed with syngeneic islets. With this experimental model the syngeneic islets, although not rejected themselves, are exposed to cytokines and in...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Korsgren, O, Jansson, L
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117063
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