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Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic α-Cells Leads to Development of Insulinomas in Mice

The pancreatic α- and β-cells are critical components in regulating blood glucose homeostasis via secretion of glucagon and insulin, respectively. Both cell types are typically localized in the islets of Langerhans. However, little is known about the roles of paracrine interactions that contribute t...

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Detalhes bibliográficos
Main Authors: Shen, H.-C. Jennifer, Ylaya, Kris, Pechhold, Klaus, Wilson, Arianne, Adem, Asha, Hewitt, Stephen M., Libutti, Steven K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940531/
https://ncbi.nlm.nih.gov/pubmed/20555035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1251
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