Targeted Disruption of Mapk14 (p38MAPKα) in Granulosa Cells and Cumulus Cells Causes Cell-Specific Changes in Gene Expression Profiles that Rescue COC Expansion and Maintain Fertility

MAPK14 (p38MAPKα) is critical for FSH and prostaglandin E (PGE)2 signaling cascades in granulosa cells (GCs) and cumulus cell-oocyte complexes (COCs) in culture, indicating that this kinase might impact follicular development and COC expansion in vivo. Because Mapk14 knockout mice are embryonic leth...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Zhilin, Fan, Heng-Yu, Wang, Yibin, Richards, JoAnne S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Endocrine Society 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940481/
https://ncbi.nlm.nih.gov/pubmed/20610537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0086
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