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Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas
The homeobox transcription factor OTX2 plays an essential role during embryonic brain development. It is normally silenced in the adult brain, but is overexpressed by genomic amplification or other mechanisms in the majority of medulloblastomas (MBs). Retinoic acids (RAs) can suppress OTX2 expressio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940451/ https://ncbi.nlm.nih.gov/pubmed/20511190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop062 |
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