Epitopes on the beta subunit of human muscle acetylcholine receptor recognized by CD4+ cells of myasthenia gravis patients and healthy subjects.

We investigated the sequence regions of the human muscle acetylcholine receptor (AChR) beta subunit forming epitopes recognized by T helper cells in myasthenia gravis (MG), using overlapping synthetic peptides, 20 residues long, which screened the sequence of the AChR beta subunit. Since CD4+ lympho...

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Publié dans:	J Clin Invest
Auteurs principaux:	Moiola, L, Karachunski, P, Protti, M P, Howard, J F, Conti-Tronconi, B M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7510715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117050
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