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Mapping myasthenia gravis–associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice
Susceptibility to myasthenia gravis (MG) is positively linked to expression of HLA-DQ8 and DR3 molecules and negatively linked to expression of the DQ6 molecule. To elucidate the molecular basis of this association, we have induced experimental autoimmune MG (EAMG) in mice transgenic for HLA-DQ8, DQ...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150946/ https://ncbi.nlm.nih.gov/pubmed/11956249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14255 |
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