Mapping myasthenia gravis–associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice

Susceptibility to myasthenia gravis (MG) is positively linked to expression of HLA-DQ8 and DR3 molecules and negatively linked to expression of the DQ6 molecule. To elucidate the molecular basis of this association, we have induced experimental autoimmune MG (EAMG) in mice transgenic for HLA-DQ8, DQ...

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Huvudupphovsmän: Yang, Huan, Goluszko, Elzbieta, David, Chella, Okita, David K., Conti-Fine, Bianca, Chan, Teh-sheng, Poussin, Mathilde A., Christadoss, Premkumar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2002
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC150946/
https://ncbi.nlm.nih.gov/pubmed/11956249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14255
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