Mapping myasthenia gravis–associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice

Susceptibility to myasthenia gravis (MG) is positively linked to expression of HLA-DQ8 and DR3 molecules and negatively linked to expression of the DQ6 molecule. To elucidate the molecular basis of this association, we have induced experimental autoimmune MG (EAMG) in mice transgenic for HLA-DQ8, DQ...

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Publié dans:	J Clin Invest
Auteurs principaux:	Yang, Huan, Goluszko, Elzbieta, David, Chella, Okita, David K., Conti-Fine, Bianca, Chan, Teh-sheng, Poussin, Mathilde A., Christadoss, Premkumar
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11956249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14255
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