Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region

Incomplete or aberrant glycosylation leading to Tn antigen (GalNAcα1-Ser/Thr) expression on human glycoproteins is strongly associated with human pathological conditions, including tumors, certain autoimmune diseases, such as the idiopathic IgA nephropathy, and may modulate immune homeostasis. In ad...

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Main Authors: Bolscher, Jan G.M., Brevoord, Judith, Nazmi, Kamran, Ju, Tongzhong, Veerman, Enno C.I., van Wijk, Joanna A. E., Cummings, Richard D., van Die, Irma
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940223/
https://ncbi.nlm.nih.gov/pubmed/20719305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.07.022
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