Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression

Proteinase 3 (PR3) is a major autoantigen in anti-neutrophil cytoplasmic antibodies (ANCA)-associated systemic vasculitis (AASV), and the proportion of neutrophils expressing PR3 on their membrane (mPR3(+)) is increased in AASV. We have shown recently that mPR3 and CD177 are expressed on the same ce...

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Bibliographic Details
Main Authors: Abdgawad, M, Gunnarsson, L, Bengtsson, A A, Geborek, P, Nilsson, L, Segelmark, M, Hellmark, T
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
Subjects:
Translational Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940153/
https://ncbi.nlm.nih.gov/pubmed/20491791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04154.x
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