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Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis

Anti-neutrophil cytoplasmic antibodies against proteinase 3 (PR3-ANCA) are used as diagnostic tools for patients with small vessel vasculitis (AASV). We have produced chimeric mouse/human PR3 molecules and investigate changes in reactivity over time and the possible relationship between epitope spec...

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Détails bibliographiques
Auteurs principaux: Selga, D, Segelmark, M, Gunnarsson, L, Hellmark, T
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883101/
https://ncbi.nlm.nih.gov/pubmed/20059480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.04063.x
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