Expression and functional profiling of neprilysin, insulin degrading enzyme and endothelin converting enzyme in prospectively studied elderly and Alzheimer’s brain

The brain steady state level of Aβ is determined by the balance between its production and removal, the latter through egress across blood and CSF barriers as well as Aβ degradation. The major Aβ degrading enzymes are neprilysin (NEP), insulin degrading enzyme (IDE) and endothelin converting enzyme...

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Huvudupphovsmän: Wang, Suqing, Wang, Rui, Chen, Lang, Bennett, David A., Dickson, Dennis W., Wang, Deng-Shun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939954/
https://ncbi.nlm.nih.gov/pubmed/20663017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06899.x
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