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β-Amyloid Degradation and Alzheimer's Disease

Extensive β-amyloid (Aβ) deposits in brain parenchyma in the form of senile plaques and in blood vessels in the form of amyloid angiopathy are pathological hallmarks of Alzheimer's disease (AD). The mechanisms underlying Aβ deposition remain unclear. Major efforts have focused on Aβ production,...

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Detalhes bibliográficos
Main Authors: Wang, Deng-Shun, Dickson, Dennis W., Malter, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559921/
https://ncbi.nlm.nih.gov/pubmed/17047308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/JBB/2006/58406
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