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Effects of 4-Hydroxy-Nonenal and Amyloid-β on Expression and Activity of Endothelin Converting Enzyme and Insulin Degrading Enzyme in SH-SY5Y Cells

The cerebral accumulation of amyloid-β (Aβ) is a consistent feature of and likely contributor to the development of Alzheimer’s disease (AD). In addition to dysregulated production, increasing experimental evidence suggests reduced catabolism plays an important role in Aβ accumulation. Although endo...

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Detalhes bibliográficos
Main Authors: Wang, Rui, Wang, Suqing, Malter, James S., Wang, Deng-Shun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819406/
https://ncbi.nlm.nih.gov/pubmed/19363254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1066
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