Neutralisation of uPA with a Monoclonal Antibody Reduces Plasmin Formation and Delays Skin Wound Healing in tPA-Deficient Mice

BACKGROUND: Proteolytic degradation by plasmin and metalloproteinases is essential for epidermal regeneration in skin wound healing. Plasminogen deficient mice have severely delayed wound closure as have mice simultaneously lacking the two plasminogen activators, urokinase-type plasminogen activator...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Jögi, Annika, Rønø, Birgitte, Lund, Ida K., Nielsen, Boye S., Ploug, Michael, Høyer-Hansen, Gunilla, Rømer, John, Lund, Leif R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939870/
https://ncbi.nlm.nih.gov/pubmed/20856796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012746
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items