Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm(†)

BACKGROUND: Successful gametogenesis requires the establishment of an appropriate epigenetic state in developing germ cells. Nevertheless, an association between abnormal spermatogenesis and epigenetic disturbances in germline-specific genes remains to be demonstrated. METHODS: In this study, the DN...

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Detalhes bibliográficos
Main Authors: Navarro-Costa, Paulo, Nogueira, Paulo, Carvalho, Marta, Leal, Fernanda, Cordeiro, Isabel, Calhaz-Jorge, Carlos, Gonçalves, João, Plancha, Carlos E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939755/
https://ncbi.nlm.nih.gov/pubmed/20685756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/deq200
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