Ivermectin Antagonizes Ethanol Inhibition in Purinergic P2X4 Receptors

ATP-gated purinergic P2X4 receptors (P2X4Rs) are expressed in the central nervous system and are sensitive to ethanol at intoxicating concentrations. P2XRs are trimeric; each subunit consists of two transmembrane (TM) α-helical segments, a large extracellular domain, and intracellular amino and carb...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Asatryan, Liana, Popova, Maya, Perkins, Daya, Trudell, James R., Alkana, Ronald L., Davies, Daryl L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2010
Gaiak:
Neuropharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939657/
https://ncbi.nlm.nih.gov/pubmed/20543096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.167908
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