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Ivermectin Antagonizes Ethanol Inhibition in Purinergic P2X4 Receptors
ATP-gated purinergic P2X4 receptors (P2X4Rs) are expressed in the central nervous system and are sensitive to ethanol at intoxicating concentrations. P2XRs are trimeric; each subunit consists of two transmembrane (TM) α-helical segments, a large extracellular domain, and intracellular amino and carb...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939657/ https://ncbi.nlm.nih.gov/pubmed/20543096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.167908 |
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