In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction (HIT qRT-PCR)

BACKGROUND: While increasing numbers of small interfering RNA (siRNA) therapeutics enter into clinical trials, the quantification of siRNA from clinical samples for pharmacokinetic studies remains a challenge. This challenge is even more acute for the quantification of chemically modified and formul...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Landesman, Yosef, Svrzikapa, Nenad, Cognetta, Armand, Zhang, Xuemei, Bettencourt, Brian R, Kuchimanchi, Satya, Dufault, Keri, Shaikh, Sarfraz, Gioia, Maple, Akinc, Akin, Hutabarat, Renta, Meyers, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939650/
https://ncbi.nlm.nih.gov/pubmed/20731861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-1-16
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados