Molecular Determinants for Competitive Inhibition of α4β2 Nicotinic Acetylcholine Receptors

The Erythrina alkaloids erysodine and dihydro-β-erythroidine (DHβE) are potent and selective competitive inhibitors of α4β2 nicotinic acetylcholine receptors (nAChRs), but little is known about the molecular determinants of the sensitivity of this receptor subtype to inhibition by this class of anta...

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Main Authors: Iturriaga-Vásquez, Patricio, Carbone, Annalisa, García-Beltrán, Olimpo, Livingstone, Phil D., Biggin, Philip C., Cassels, Bruce K., Wonnacott, Susan, Zapata-Torres, Gerald, Bermudez, Isabel
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939478/
https://ncbi.nlm.nih.gov/pubmed/20547737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.065490
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