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Tumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complementary cMORF effector
AIM: Using the antiCEA antibody MN14, a LS174T mouse tumor model has been successfully targeted with (99m)Tc for imaging and (188)Re for radiotherapy by a MORF/cMORF pretargeting strategy. This investigation evaluated the antiTAG-72 antibody CC49 as an alternative to MN14 for this application. METHO...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939249/ https://ncbi.nlm.nih.gov/pubmed/20639818 |
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