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Pretargeting CWR22 prostate tumor in mice with MORF-B72.3 antibody and radiolabeled cMORF

PURPOSE: We have now applied our MORF/cMORF pre-targeting technology to the targeting of CWR22 prostate tumor in nude mice. METHODS: The antiTAG-72 antibody B72.3 was conjugated with an 18 mer MORF while the cMORF was radiolabeled with (99m)Tc. The specific binding of the antibody to the CWR22 cells...

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Hlavní autoři: Liu, Guozheng, Dou, Shuping, Pretorius, P. Hendrik, Liu, Xinrong, Rusckowski, Mary, Hnatowich, Donald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259287/
https://ncbi.nlm.nih.gov/pubmed/17909792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-007-0606-z
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