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Replacing (99m)Tc with (111)In improves MORF/cMORF pretargeting by reducing intestinal accumulation

PURPOSE: To reduce accumulation in the abdomen by MORF/cMORF pretargeting, (111)In was compared to (99m)Tc as the radiolabel. PROCEDURES: After receiving either (99m)Tc (MAG3)-cMORF or (111)In (DTPA)-cMORF, normal mice were imaged and sacrificed for pharmacokinetics. Thereafter, tumored mice were pr...

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Detalles Bibliográficos
Main Authors: Liu, Guozheng, Cheng, Dengfeng, Dou, Shuping, Chen, Xiangji, Liang, Minmin, Pretorius, P Hendrik, Rusckowski, Mary, Hnatowich, Donald J
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720424/
https://ncbi.nlm.nih.gov/pubmed/19326173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0209-0
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