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Distinct Roles of Cytolytic Effector Molecules for Antigen-restricted Killing by CTL in vivo
Cytotoxic T lymphocytes (CTL) represent one of the front lines of defense for the immune system, killing virus-infected and tumor-transformed cells. CTL use at least two mechanisms to induce apoptosis in their targets, one mediated by perforin and granzymes, and the other triggered by the death liga...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939217/ https://ncbi.nlm.nih.gov/pubmed/20309009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.37 |
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