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Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42
Cytolytic effectors polarize toward target cells for effective killing and IFN-γ secretion. The spatiotemporal features of this polarization and their importance for cytolysis have not been resolved. In cytotoxic T cells and natural killer (NK) cells, transient polarization was consistently associat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900700/ https://ncbi.nlm.nih.gov/pubmed/20547841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913422107 |
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