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Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42

Cytolytic effectors polarize toward target cells for effective killing and IFN-γ secretion. The spatiotemporal features of this polarization and their importance for cytolysis have not been resolved. In cytotoxic T cells and natural killer (NK) cells, transient polarization was consistently associat...

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Bibliografski detalji
Glavni autori: Sinai, Parisa, Nguyen, Chau, Schatzle, John D., Wülfing, Christoph
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900700/
https://ncbi.nlm.nih.gov/pubmed/20547841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913422107
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