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Epigenetic Mechanisms Regulate Stem Cell Expressed Genes Pou5f1 and Gfra1 in a Male Germ Cell Line
Male fertility is declining and an underlying cause may be due to environment-epigenetic interactions in developing sperm, yet nothing is known of how the epigenome controls gene expression in sperm development. Histone methylation and acetylation are dynamically regulated in spermatogenesis and are...
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| Format: | Artigo |
| Jezik: | Inglês |
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Public Library of Science
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939054/ https://ncbi.nlm.nih.gov/pubmed/20856864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012727 |
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