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Epigenetic Mechanisms Regulate Stem Cell Expressed Genes Pou5f1 and Gfra1 in a Male Germ Cell Line

Male fertility is declining and an underlying cause may be due to environment-epigenetic interactions in developing sperm, yet nothing is known of how the epigenome controls gene expression in sperm development. Histone methylation and acetylation are dynamically regulated in spermatogenesis and are...

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Detalhes bibliográficos
Main Authors: Godmann, Maren, May, Erin, Kimmins, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939054/
https://ncbi.nlm.nih.gov/pubmed/20856864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012727
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