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Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice

Expression levels of the pluripotency determinant, POU5F1, are tightly regulated to ensure appropriate differentiation during early embryogenesis. POU5F1 is also present in the spermatogonial stem cell/progenitor cell population in mice and it is downregulated as spermatogenesis progresses. To test...

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Detalhes bibliográficos
Publicado no:Reproduction
Main Authors: Zheng, Yu, Phillips, LeAnna J., Hartman, Rachel, An, Junhui, Dann, Christina T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003728/
https://ncbi.nlm.nih.gov/pubmed/27486267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-16-0140
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