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The M-domain Controls the Hsp104 Protein-remodeling Activity in an Hsp70/Hsp40-dependent Manner

Yeast Hsp104 is a ring-forming, ATP-dependent protein disaggregase that, together with the cognate Hsp70 chaperone system, has the remarkable ability to rescue stress damaged proteins from a previously aggregated state. Both up-stream and down-stream functions for the Hsp70 system have been reported...

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Autors principals: Sielaff, Bernhard, Tsai, Francis T.F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938849/
https://ncbi.nlm.nih.gov/pubmed/20654624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.030
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