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A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58

Posttranslational SUMO modification is an important mechanism of regulating protein function, especially in the cell nucleus. The nucleolus is the subnuclear organelle responsible for rRNA synthesis, processing, and assembly of the large and small ribosome subunits. Here, we have used SILAC-based qu...

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書誌詳細
主要な著者: Westman, Belinda J., Verheggen, Céline, Hutten, Saskia, Lam, Yun Wah, Bertrand, Edouard, Lamond, Angus I.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938476/
https://ncbi.nlm.nih.gov/pubmed/20797632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.025
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