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Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

BACKGROUND: The nucleolus is a subnuclear organelle in which rRNAs are transcribed, processed, and assembled with ribosomal proteins into ribosome subunits. Mass spectrometry combined with pulsed incorporation of stable isotopes of arginine and lysine was used to perform a quantitative and unbiased...

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Detalles Bibliográficos
Autores principales: Lam, Yun Wah, Lamond, Angus I., Mann, Matthias, Andersen, Jens S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885954/
https://ncbi.nlm.nih.gov/pubmed/17446074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.03.064
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