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Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells
Forodesine, a purine nucleoside phosphorylase inhibitor, displays in vitro activity in chronic lymphocytic leukemia (CLL) cells in presence of dGuo, which is the basis for an ongoing clinical trial in patients with fludarabine-refractory CLL. Initial clinical data indicate forodesine has significant...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938131/ https://ncbi.nlm.nih.gov/pubmed/20442367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246199 |
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