Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes

Systematic study of cell signaling networks increasingly involves high throughput proteomics, transcriptional profiling, and automated literature mining with the aim of assembling large scale interaction networks. In contrast, functional analysis of cell signaling usually focuses on a much smaller s...

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Detalhes bibliográficos
Main Authors: Alexopoulos, Leonidas G., Saez-Rodriguez, Julio, Cosgrove, Benjamin D., Lauffenburger, Douglas A., Sorger, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938121/
https://ncbi.nlm.nih.gov/pubmed/20460255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000406
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