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Mucosal priming of newborn mice with S. Typhi Ty21a expressing anthrax protective antigen (PA) followed by parenteral PA-boost induces B and T cell-mediated immunity that protects against infection bypassing maternal antibodies

The currently licensed anthrax vaccine has several limitations and its efficacy has been proven only in adults. Effective immunization of newborns and infants requires adequate stimulation of their immune system, which is competent but not fully activated. We explored the use of the licensed live at...

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Bibliografske podrobnosti
Main Authors: Ramirez, Karina, Ditamo, Yanina, Galen, James E., Baillie, Les W. J., Pasetti, Marcela F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938045/
https://ncbi.nlm.nih.gov/pubmed/20619377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.06.089
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