Mucosal or Parenteral Administration of Microsphere-Associated Bacillus anthracis Protective Antigen Protects against Anthrax Infection in Mice

Existing licensed anthrax vaccines are administered parenterally and require multiple doses to induce protective immunity. This requires trained personnel and is not the optimum route for stimulating a mucosal immune response. Microencapsulation of vaccine antigens offers a number of advantages over...

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Bibliographische Detailangaben
Hauptverfasser: Flick-Smith, Helen C., Eyles, Jim E., Hebdon, Richard, Waters, Emma L., Beedham, Richard J., Stagg, Tony J., Miller, Julie, Alpar, H. Oya, Baillie, Les W. J., Williamson, E. Diane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127835/
https://ncbi.nlm.nih.gov/pubmed/11895967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.2022-2028.2002
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