Peptide Ligands Selected with CD4-Induced Epitopes on Native Dualtropic HIV-1 Envelope Proteins Mimic Extracellular Coreceptor Domains and Bind to HIV-1 gp120 Independently of Coreceptor Usage

During HIV-1 entry, binding of the viral envelope glycoprotein gp120 to the cellular CD4 receptor triggers conformational changes resulting in exposure of new epitopes, the highly conserved CD4-induced (CD4i) epitopes that are essential for subsequent binding to chemokine receptor CCR5 or CXCR4. Due...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dervillez, Xavier, Klaukien, Volker, Dürr, Ralf, Koch, Joachim, Kreutz, Alexandra, Haarmann, Thomas, Stoll, Michaela, Lee, Donghan, Carlomagno, Teresa, Schnierle, Barbara, Möbius, Kalle, Königs, Christoph, Griesinger, Christian, Dietrich, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937783/
https://ncbi.nlm.nih.gov/pubmed/20660187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00165-10
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados