Mimicking Protein–Protein Interactions through Peptide–Peptide Interactions: HIV-1 gp120 and CXCR4

We have recently designed a soluble synthetic peptide that functionally mimics the HIV-1 coreceptor CXCR4, which is a chemokine receptor that belongs to the family of seven-transmembrane GPCRs. This CXCR4 mimetic peptide, termed CX4-M1, presents the three extracellular loops (ECLs) of the receptor....

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Bibliografiske detaljer
Main Authors: Groß, Andrea, Möbius, Kalle, Haußner, Christina, Donhauser, Norbert, Schmidt, Barbara, Eichler, Jutta
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760305/
https://ncbi.nlm.nih.gov/pubmed/24027570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00257
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