Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX

Adenovirus (Ad) vectors are the most commonly used system for gene therapy applications, due in part to their ability to infect a wide array of cell types and tissues. However, many therapies would benefit from the ability to target the Ad vector only to specific cells, such as tumor cells for cance...

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Hlavní autoři: Poulin, Kathy L., Lanthier, Robert M., Smith, Adam C., Christou, Carin, Risco Quiroz, Milagros, Powell, Karen L., O'Meara, Ryan W., Kothary, Rashmi, Lorimer, Ian A., Parks, Robin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Gene Delivery
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937758/
https://ncbi.nlm.nih.gov/pubmed/20631131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02665-09
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