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Release of Genotype 1 Hepatitis E Virus from Cultured Hepatoma and Polarized Intestinal Cells Depends on Open Reading Frame 3 Protein and Requires an Intact PXXP Motif

Hepatitis E virus genotype 1 strain Sar55 replicated in subcloned Caco-2 intestinal cells and Huh7 hepatoma cells that had been transfected with in vitro transcribed viral genomes, and hepatitis E virions were released into the culture medium of both cell lines. Virus egress from cells depended on o...

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Bibliografiske detaljer
Main Authors: Emerson, Suzanne U., Nguyen, Hanh T., Torian, Udana, Burke, Danielle, Engle, Ronald, Purcell, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937629/
https://ncbi.nlm.nih.gov/pubmed/20610720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00593-10
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