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T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice

A dysregulated innate immune response and exuberant cytokine/chemokine expression are believed to be critical factors in the pathogenesis of severe acute respiratory syndrome (SARS), caused by a coronavirus (SARS-CoV). However, we recently showed that inefficient immune activation and a poor virus-s...

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מידע ביבליוגרפי
Main Authors: Zhao, Jincun, Zhao, Jingxian, Perlman, Stanley
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937604/
https://ncbi.nlm.nih.gov/pubmed/20610717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01049-10
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